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Jens Zimmermann Selected Research

Adrenomedullin

11/2021Safety and tolerability of non-neutralizing adrenomedullin antibody adrecizumab (HAM8101) in septic shock patients: the AdrenOSS-2 phase 2a biomarker-guided trial.
11/2020Targeting Endothelial Dysfunction in Eight Extreme-Critically Ill Patients with COVID-19 Using the Anti-Adrenomedullin Antibody Adrecizumab (HAM8101).
1/2019A double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentration (AdrenOSS-2).

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Jens Zimmermann Research Topics

Disease

2Shock
11/2021 - 11/2020
2Sepsis (Septicemia)
11/2021 - 11/2020
2Septic Shock (Toxic Shock Syndrome)
11/2021 - 01/2019
2Critical Illness (Critically Ill)
11/2020 - 01/2019
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
11/2020
1COVID-19
11/2020
1Inflammation (Inflammations)
11/2020
1Pulmonary Embolism
11/2020
1Acute Kidney Injury (Acute Renal Failure)
11/2020
1Angioedema
08/2010
1Hereditary Angioedemas
08/2010
1Pain (Aches)
01/2007
1Hemorrhoids
01/2007
1Fistula
01/2007
1Proctitis
01/2007

Drug/Important Bio-Agent (IBA)

3AdrenomedullinIBA
11/2021 - 01/2019
3enibarcimabIBA
11/2021 - 01/2019
2Biomarkers (Surrogate Marker)IBA
11/2021 - 01/2019
1Therapeutic UsesIBA
01/2019
1icatibantIBA
08/2010
1Tranexamic Acid (AMCA)FDA Link
08/2010
1Bradykinin Receptor AntagonistsIBA
08/2010
1Lidocaine (Xylocaine)FDA LinkGeneric
01/2007
1Ointments (Pastes)IBA
01/2007

Therapy/Procedure

1Mechanical Ventilators (Ventilator)
11/2021
1Renal Replacement Therapy (Therapies, Renal Replacement)
11/2020